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ds2a mkii constant voltage isolated stimulator  (Digitimer North America LLC)


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    Digitimer North America LLC ds2a mkii constant voltage isolated stimulator
    Ds2a Mkii Constant Voltage Isolated Stimulator, supplied by Digitimer North America LLC, used in various techniques. Bioz Stars score: 96/100, based on 504 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/constant+voltage+stimulator+ds2a-mkii/Stimulator+Mounting+Frame+-+Digitimer/pmc06307858-228-19-24
    Average 96 stars, based on 504 article reviews
    ds2a mkii constant voltage isolated stimulator - by Bioz Stars, 2026-09
    96/100 stars

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    Article Title: Nitric oxide mediates activity-dependent change to synaptic excitation during a critical period in Drosophila
    Article Snippet: A 2.3 V DC pulse for 2 s, created by a constant voltage generator (DS2A‐mkII, Digitimer Ltd., Welwyn Garden City, Hertfordshire, UK), was applied.

    Article Title: Nitric oxide mediates activity-dependent change to synaptic excitation during a critical period in Drosophila.
    Article Snippet: A 2.3 V DC pulse for 2 s, created by a constant voltage generator (DS2A‐mkII, Digitimer Ltd., Welwyn Garden City, Hertfordshire, UK), was applied.

    Isolation:

    Article Title: Experimental and real-world evidence supporting the computational repurposing of bumetanide for APOE4 -related Alzheimer's disease
    Article Snippet: .. For input/output recording studies, field post-synaptic potentials (fPSPs) were elicited by orthodromic stimulation of Schaffer collaterals by concentric bipolar stimulating electrode (FHC, Inc., USA) connected to a constant voltage isolated stimulator (DS2A-MKII, Digitimer North America) and placed in CA2 stratum radiatum. fPSPs were recorded with a glass borosilicate microelectrode filled with ACSF and placed in CA1 stratum radiatum. .. Signals were sampled and digitized by MultiClamp 700B amplifier and Digidata 1550B1 acquisition system with pClamp10 software (Molecular Devices, USA), and analyzed using IgorPro6 software (Wavemetrics Inc., USA) running custom macros. fPSP slopes were analyzed as the linear fit slope values between 10% and 90% of fPSP peak.

    Article Title: Release probability increases towards distal dendrites boosting high-frequency signal transfer in the rodent hippocampus
    Article Snippet: .. To identify active synapses relatively fast (10 Hz) frame scans of the local dendrites were viewed whilst three 100 ms square pulses of 2–10 V were delivered with a 25 ms inter-stimulus interval using a constant voltage isolated stimulator (model DS2A-mkII, Digitimer Ltd, Welwyn Garden City, UK). ..

    Article Title: Neurons require glucose uptake and glycolysis in vivo.
    Article Snippet: For recordings, slices were transferred to a submerged chamber (RC-27LD, Warner Instruments, USA) where they were continuously superfused on both sides with oxygenated ACSF at 32 C at a flow rate of 10 mL/min. .. Local Field Potentials (LFPs) were elicited by orthodromic stimulation of Schaffer collaterals by concentric bipolar stimulating electrode (FHC, Inc., USA) connected to a constant voltage isolated stimulator (DS2A-MKII, Digitimer North America) and placed in CA2 str. radiatum. ..

    Article Title: Methods for treating APOE4/4-associated disorders
    Article Snippet: For recordings, slices were transferred to a submerged chamber (RC-27LD, Warner Instruments, USA) where they were continuously perfused on both sides with oxygenated ACSF at 32° C. at a flow rate of 10 mL/min. .. Field post-synaptic potentials (fPSPs) were elicited by orthodromic stimulation of Schaffer collaterals by concentric bipolar stimulating electrode (FHC, Inc., USA) connected to a constant voltage isolated stimulator (DS2A-MKII, Digitimer North America) and placed in CA2 stratum radiatum. fPSPs were recorded with a glass borosilicate microelectrode filled with ACSF and placed in CA1 stratum radiatum. .. Signals were sampled and digitized by MultiClamp 700B amplifier and Digidata 1550B1 acquisition system with pClamp10 software (Molecular Devices, USA), and analyzed using IgorPro6 software (Wavemetrics Inc., USA) running custom macros. fPSP slopes were analyzed as the linear fit slope values between 10% and 90% of fPSP peak.

    Article Title: Mechanisms of APOE4-Driven Alzheimer’s Disease Pathogenesis and Related Therapeutic Approaches
    Article Snippet: .. For input/output recording studies, local field post-synaptic potentials (fPSPs) were elicited by orthodromic stimulation of Schaffer collaterals by concentric bipolar stimulating electrode (FHC) connected to a constant voltage isolated stimulator (DS2A-MKII, Digitimer North America) and placed in CA2 stratum radiatum. fPSPs were recorded with a glass borosilicate microelectrode filled with ACSF and placed in CA1 stratum radiatum. .. Signals were sampled and digitized by MultiClamp 700B amplifier and Digidata 1550B1 acquisition system with pClamp10 software (Molecular Devices), and analyzed using IgorPro6 software (Wavemetrics) running custom macros. fPSP slopes were analyzed as the linear fit slope values between 10% and 90% of fPSP peak.



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